Protective effect of spermatogenic activity of Withania Somnifera (Ashwagandha) in galactose stressed mice
نویسندگان
چکیده
In recent years, population is facing many health problems like chronic non-communicable diseases like Cancer, Stroke, Diabetes, Cardiovascular disorders and Reproductive disorders fro very early age. Urbanization and mechanization have changed the life style of the whole population which has resulted in greater exposure to pollution, high consumption of salt and fat containing food, low physical activity and stress. Withania may be having antioxidant property; protecting male reproductive organs from ROS and can avoid infertility. The overall findings may be helpful to the population not only to treat infertility but also to maintain normal sexual life.
منابع مشابه
Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study
Ashwagandha (Withania somnifera) has been described in traditional Indian Ayurvedic medicine as an aphrodisiac that can be used to treat male sexual dysfunction and infertility. This pilot study was conducted to evaluate the spermatogenic activity of Ashwagandha root extract in oligospermic patients. Forty-six male patients with oligospermia (sperm count < 20 million/mL semen) were enrolled and...
متن کاملEffects of glycowithanolides on lipid peroxidation and lipofuscinogenesis in male reproductive organs of mice
BACKGROUND Glycowithanolides (Withaferin A), is one of the main withanolides active principle isolated from plant Withania somnifera and is claimed that it possess the aphrodisiac, sedative, rejuvenate and life prolonging properties. OBJECTIVE In the present investigation, antioxidant activity of active principles of Withania somnifera was tested against D-galactose induced oxidative stress i...
متن کاملWithania Somnifera L Root Extract Ameliorates Toxin Induced Cytotoxicity
In this study the use of plants for medicinal purpose used locally in the treatment of various diseases and we examined for their antioxidant activity. Therefore, the present investigation is part of continuing programme related to the biochemical screening of local plants used in Ancient Indian Medicine, Ayurveda, Siddha and Yunani. An Aqueous root extract of Withania Somnifera (L.) Dunal (Ash...
متن کاملEffect of Withania somnifera Dunal root extract against pentylenetetrazol seizure threshold in mice: possible involvement of GABAergic system.
Withania somnifera (ashwagandha) is a widely used herb in the Ayurvedic system of medicine. The objective of the present study was to elucidate the effect of W. somnifera root extract (Ws) alone or in combination with exogenous gamma-amino butyric acid (GABA), a GABA receptor agonist or with diazepam, a GABA receptor modulator against pentylenetetrazol (PTZ, iv) seizure threshold in mice. Minim...
متن کاملP01.44. In vivo immune modulating effects of Ashwagandha (Withania somnifera)
Purpose The herb Ashwagandha (Withania somnifera, Dunal), has been used for centuries in Ayurveda as rasayana – promoter of longevity, well-being, and disease prevention. Traditional use combines the herb with a carrier substance called “anupana,” believed to help aid in bioavailability and absorption. To compare the effects of Ashwagandha root extract plus anupana on human immune activation to...
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